THCP, a LOT more potent than THC?

Cannabinoid research has only recently begun, but THCP is one of the most potent cannabinoids discovered so far.
You are likely already familiar with delta 9 THC, the chief psychoactive component in cannabis. There are actually dozens of distinct forms of THC. Some are far more powerful than others. Here, we’ll talk about THCP, a cannabinoid that is thought to be more than 30 times more potent than delta-9 THC and the most powerful member of the THC class.


THCP, which stands for “tetrahydrocannabiphorol” and is also called “(-)-Trans-9-tetrahydrocannabiphorol” in science, is a natural cannabinoid that is similar to THC and is found in some types of cannabis. THCP is believed to be 33 times more active on Cannabinoid 1 (CB1) receptors than THC, which gives THCP a strong, euphoric high. THCP is found naturally in cannabis plants but in very low concentrations.


This is an interesting question, and we don’t have a concrete answer yet.
THCP is still a newcomer to the cannabis industry, and scientists are still conducting extensive research for medical purposes. THCP has the same effects as THC but with an added punch. It may also be a more effective sleep aid for those who have insomnia. Pain relief will almost certainly be enhanced. So far, the following are some of the recognized benefits of using THCP:

Relieving aches and pains
Increase in appetite


What is it about THCP that makes it so psychoactive?
The size and shape of the molecule influence the effects of cannabis.

Carbon atoms significantly influence cannabis’s ability to produce psychoactive effects. Researchers have previously demonstrated that THC must have at least three carbons on the alkyl-side chain to have any psychoactive effects. The greater the number of carbons, the greater the effect (there are limitations to this).

THCP has seven carbon atoms instead of 5 in its carbon chain.

THC is part of a five-alkyl carbon chain, which you may be familiar with if you’re acquainted with other cannabinoids like CBG, CBD, Delta 8, etc. This type of carbon chain can produce psychoactive effects on certain levels.

Longer alkyl chain phytocannabinoids appear to bind more readily with CB-1 receptors in the body’s central nervous system. The seven-carbon alkyl chain in THCP seems to have a more substantial binding effect on a cannabinoid receptor in the brain.
This means that more THCP is absorbed by the gut and gets to the brain than regular THC.
It is absolutely okay if none of this makes sense to you. The important thing to understand is that THC-P is extremely potent.


It has been reported that THCP has a high affinity for binding with CB1 receptors, which are mostly found in the brain and body. These receptors help regulate anxiety, stress, pain relief, happiness, and other emotions. Also, these new studies have shown that THCP may be five to ten times more active than THC on the CB2 receptors. These receptors help control inflammation and pain, boost our immune response to pathogens, and stop bone loss as we age.


No, THCP is not made in a lab. It is found naturally in cannabis. THCP is one of cannabis’s identified 140 (or more) phytocannabinoids. The amount of THCP found in nature is much less than 0.1 percent. Like the FM2 strain grown in Italy, some hemp plants have almost 0.1% THCP. In comparison, marijuana has 25–30% THC, while hemp has 0.3 percent or less. CBD levels in hemp are typically between 20 and 30 percent, while levels in marijuana are around 15 percent.
Due to the extremely low concentration of THCP in cannabis, researchers must artificially recreate it to study it further.

So, if this comes from the cannabis or hemp plants, how do they extract THCP?

The first paper documenting THCP extraction from a cannabis plant was published in 2019 and was later adapted to develop the current manufacturing process.
Without delving so much into chemistry, all cannabinoids found in cannabis and hemp plants start as CBGA. CBGA then undergoes an enzymatic reaction with other acidic compounds in cannabis to produce THC AND CBD. THC and CBD are the starting material for the production of THCP, implying that they can be effectively derived from hemp.
The cannabis or hemp plant then slowly converts THCPA to THCP via a process known as decarboxylation.


Yes, it can. The effects of THCP are seriously strong. It is likely to produce a much more potent set of psychoactive effects than Delta-9. While we don’t have any sure answers as to how THCP works in the human body, it is fair to assume that it gets you high.


Many THCP users say that the effects are an enhanced version of THC. It’s more potent (almost psychoactive) and requires fewer doses to experience similar effects to THC.
The original paper from 2019 about the first time THCP was found in a cannabis plant says that it relieves pain and suggests that THCP might have many of the same medical effects as THC. However, although THCP and THC may have many of the same benefits, there is one big difference between the two. Because THCP is 30 times more biologically active than THC, its effects are also 30 times stronger. This means that THCP and THC will be given in very different amounts.
For this, you should be careful, especially if you have ever had adverse reactions from THC, such as anxiety, memory loss, or paranoia.


There is not much information on the effect of THCP on the brain. However, anecdotal evidence suggests that this cannabinoid has the same common effects as delta 9 THC, but with more stimulating action and a stronger alteration in visual and auditory perception.
THCP is not hallucinogenic, the sensation it gives is often described as leaning towards the psychedelic.
You will not see things, leave your body, or experience any typical psychedelic effects, but it will shift your perception away from the center. You may become interested in things you would not normally be interested in, music may sound different than you remember, and colors may appear brighter than they were before. The side effects are also heightened.


It takes about an hour for edible forms of THCP, such as gummies or tinctures, to take effect. The effects intensify over the next hour and peak by hour three. These effects are strongest for about 2 hours before slowly fading. The overall experience lasts 4 to 6 hours.
THCP inhaled forms, such as vapes or THCP flowers, kick in much faster within 15 minutes. A peak experience is reached after one hour and begins to taper off after about two hours. The effects of inhaling THCP last between 3 and 5 hours.


The side effects of THCP are still unclear. However, since THCP is similar to THC, we can say that the two share similar side effects, with THCP’s side effects being more noticeable. The following are some common side effects of THC:

Nausea or Vomiting
Dry Mouth
Red Eyes
Fatigue or Lethargy

Since THCP is said to bind to your CB1 receptor more strongly, we think the side effects may be more robust.


THCP is a cannabinoid that will play an essential role in the development of cannabinoid science in the years to come.

The keynote is that THCP is a more potent, legal form of delta 9 THC.

Because of the difficult manufacturing process, THCP and lesser-known cannabinoids are hard to come by.

We here at DENEX take time digging into cannabinoids and we know what cannabinoid compounds are currently in the buzz. So, if you are interested in trying THCP, give our team a call!

Our THCP has been tested by trusted laboratories to ensure what you are getting is of the highest quality. However, due to legality issues in some states with THC-derived products, it is best to double-check if this is something you can obtain.

You can also subscribe to our newsletter to get the most recent offers on our cannabinoid products.


Stone, Emma Francis. (2021, December 23). The Complete Guide to THCP.  Leafreport.

Dispensaries News. (2020, Feburary 19). Scientists Discover New Compound in Marijuana That Could Provide Health Benefits.

Winkler, Natasha. (2020, February 20). Will THCP Actually Get You 30x Higher Than THC?  Veriheal.

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